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Operational
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NGIS_PROD_Test_Ordering
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NGIS_PROD_SFTP
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NGIS_PROD_CVA
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NGIS_PROD_IGV
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NGIS_PROD_Cancer_DSS
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NGIS_UAT_Environment
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General_Service_Updates_NGIS_UAT
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NGIS_UAT_Test_Selection
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NGIS_UAT_Test_Ordering
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NGIS_UAT_SFTP
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NGIS_UAT_M.I.Portal
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NGIS_UAT_Interpretation_Portal
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NGIS_UAT_CIP_API
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NGIS_UAT_CVA
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NGIS_UAT_IGV
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NGIS_UAT_Congenica
Operational
NGIS_UAT_Cancer_DSS
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Third Party Integrator
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Third Party Integrator - Production
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Third Party Integrator - UAT
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Third Party Integrator - SIT
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100K_Applications
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100K_Interpretation_Portal
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100K_CIP-API
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100K_SNP
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100K_Congenica
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General_Service_Updates_100K_Applications
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Cloud_RE
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Atlassian_Suite
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GE_Jira_Service_Desk
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PanelApp
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Generation Study (Newborns)
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Generation Study Portal
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Generation Study Website
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Generation Study CRM
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Variant Review Tool
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Tableau
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Tableau_Production_External (Coming Soon)
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Degraded Performance
Partial Outage
Major Outage
Maintenance
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No downtime recorded on this day.
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had a major outage.
had a partial outage.
Scheduled Maintenance
NGIS Production Environment: Congenica Case Deletion - 19 March 2026 Mar 19, 2026 09:00-17:00 GMT
Dear Congenica User,
This is a reminder that GEL will be deleting cases from Congenica on a regular basis. The cases that will be marked for deletion will be the ones that have been closed for 2 weeks in the Interpretation Portal, this is regardless of the amount of time that it has been in Congenica. Closed is defined as the report/summary of findings and exit questionnaire being completed by the user.
The next set of deletions will take place on the Thursday, 19 March 2026.
If you wish to keep a case in Congenica, we advise that you inform the Genomics England Service Desk at least 3 days in advance of the 2 week mark for your case.
Posted on Mar 11, 2026 - 17:08 GMT
This is a reminder that GEL will be deleting cases from Congenica on a regular basis. The cases that will be marked for deletion will be the ones that have been closed for 2 weeks in the Interpretation Portal, this is regardless of the amount of time that it has been in Congenica. Closed is defined as the report/summary of findings and exit questionnaire being completed by the user.
The next set of deletions will take place on the Thursday, 19 March 2026.
If you wish to keep a case in Congenica, we advise that you inform the Genomics England Service Desk at least 3 days in advance of the 2 week mark for your case.
Posted on Mar 11, 2026 - 17:08 GMT
Research Environment - Maintenance Notification - CloudOS Data Release Mar 19, 2026 09:00-18:00 GMT
Dear Users,
We would like to inform you of a planned release being deployed for CloudOS.
SW 6.3 Cedar Release will be deployed on Thursday, 19 March 2026 between 09:00 (GMT) and 18:00 (GMT).
Please note that we cannot ensure the normal functionality of the CloudOS application during this time.
This release will include 8 new features for CloudOS, including:
Data Science
-Publish RShiny apps from RStudio: You can now publish RShiny web apps directly from your RStudio session into your workspace. Once published, the app becomes available as a new interactive session type, making it easy for others in your workspace to launch and use.
Advanced Analytics
-Parameter Files for Nextflow Pipelines: Users can select a params file to define pipeline parameters when running a Nextflow workflow, enabling easier reuse and standardisation of configurations.
-Default Batch Queue Update: All workspaces now include a default batch queue optimised for cost and scalability, to improve job reliability and performance.
If you have any issues following this release, please let us know by raising a Service Desk ticket.
We apologise in advance for any inconvenience caused by this upgrade.
Best wishes,
Genomics England
Posted on Mar 16, 2026 - 08:54 GMT
We would like to inform you of a planned release being deployed for CloudOS.
SW 6.3 Cedar Release will be deployed on Thursday, 19 March 2026 between 09:00 (GMT) and 18:00 (GMT).
Please note that we cannot ensure the normal functionality of the CloudOS application during this time.
This release will include 8 new features for CloudOS, including:
Data Science
-Publish RShiny apps from RStudio: You can now publish RShiny web apps directly from your RStudio session into your workspace. Once published, the app becomes available as a new interactive session type, making it easy for others in your workspace to launch and use.
Advanced Analytics
-Parameter Files for Nextflow Pipelines: Users can select a params file to define pipeline parameters when running a Nextflow workflow, enabling easier reuse and standardisation of configurations.
-Default Batch Queue Update: All workspaces now include a default batch queue optimised for cost and scalability, to improve job reliability and performance.
If you have any issues following this release, please let us know by raising a Service Desk ticket.
We apologise in advance for any inconvenience caused by this upgrade.
Best wishes,
Genomics England
Posted on Mar 16, 2026 - 08:54 GMT
NGIS Production Environment: Maintenance, Regulus Increment 1.3 and Cancer DSS v6.17.0 Release Notification Mar 25, 2026 17:00-21:00 GMT
Dear all,
We would like to inform you of planned maintenance and software releases in the NGIS production environment. Regulus Increment 1.3 and CDSSv6.17.0 will be released on Wednesday, 25 March 2026 from 17:00 (GMT) to 21:00 (GMT).
The main changes in the Regulus Increment 1.3 release are:
- Fix to SNV variants filtering so that they are now sorted in ascending order
- Fix to OMIM links in IP
- Fix to Slow Page Load in Interpretation Portal
- Fix to Selecting Tier 1 or Tier 2 report event for STRs in Compound Heterozygous Case so users can see the variant
- Incorrect Tiered STR Variant Count in Interpretation Summary After Variant Selection/Deselection in Interpretation Browser
- Fix to Ordering by CNV tiers
- Fix to Transcripts are not being sent to Congenica in the GEL payload for RD cases
The CDSSv6.17.0 Release Note is now available in the 'GEL Release Documentation' folder in NHS Futures.
The main changes in the CDSSv6.17.0 release are:
- Non-pass option for VCF filter for all variants
- Variant type for somatic SVs
- Variant type for somatic CNVs
- Copy number for somatic and germline CNVs
- Sorting by genomic coordinates for all variants
- VCF filter (Pass and Non-pass options) for germline CNVs
- Flag status filter (Flag and unflagged options) for germline CNVs
Please note that all applications in the NGIS production environment will be unavailable within this timeframe.
Posted on Mar 18, 2026 - 13:43 GMT
We would like to inform you of planned maintenance and software releases in the NGIS production environment. Regulus Increment 1.3 and CDSSv6.17.0 will be released on Wednesday, 25 March 2026 from 17:00 (GMT) to 21:00 (GMT).
The main changes in the Regulus Increment 1.3 release are:
- Fix to SNV variants filtering so that they are now sorted in ascending order
- Fix to OMIM links in IP
- Fix to Slow Page Load in Interpretation Portal
- Fix to Selecting Tier 1 or Tier 2 report event for STRs in Compound Heterozygous Case so users can see the variant
- Incorrect Tiered STR Variant Count in Interpretation Summary After Variant Selection/Deselection in Interpretation Browser
- Fix to Ordering by CNV tiers
- Fix to Transcripts are not being sent to Congenica in the GEL payload for RD cases
The CDSSv6.17.0 Release Note is now available in the 'GEL Release Documentation' folder in NHS Futures.
The main changes in the CDSSv6.17.0 release are:
- Non-pass option for VCF filter for all variants
- Variant type for somatic SVs
- Variant type for somatic CNVs
- Copy number for somatic and germline CNVs
- Sorting by genomic coordinates for all variants
- VCF filter (Pass and Non-pass options) for germline CNVs
- Flag status filter (Flag and unflagged options) for germline CNVs
Please note that all applications in the NGIS production environment will be unavailable within this timeframe.
Posted on Mar 18, 2026 - 13:43 GMT
Research Environment - Maintenance Notification - High Performance Computing (HPC) Mar 29, 2026 10:00-12:00 BST
Update -
Dear research user,
The Double Helix HPC will not be available on Sunday, 29 March 2026 from 10:00 (BST) to 12:00 (BST).
Reminder: Do not start any new jobs or at least jobs that won’t complete within a week as bigmem and long queues will be closed or drained in preparation for the scheduled downtime.
You may login and resubmit your jobs from Monday, 30 March 2026.
We apologise for any inconvenience this may cause.
Best Wishes,
Genomics England
Mar 13, 2026 - 10:01 GMT
The Double Helix HPC will not be available on Sunday, 29 March 2026 from 10:00 (BST) to 12:00 (BST).
Reminder: Do not start any new jobs or at least jobs that won’t complete within a week as bigmem and long queues will be closed or drained in preparation for the scheduled downtime.
You may login and resubmit your jobs from Monday, 30 March 2026.
We apologise for any inconvenience this may cause.
Best Wishes,
Genomics England
Mar 13, 2026 - 10:01 GMT
Scheduled -
Dear research user,
The Double Helix HPC will not be available on Sunday, 29 March 2026 from 10:00 (GMT) to 12:00 (GMT).
Logins will not be possible during this time and running interactive jobs will be affected, any jobs that are still running at the start of the maintenance window will be terminated and will need to be rerun. This will include any orchestration jobs you may have running for your workflows.
In preparation please:
* save any ongoing work
* terminate (using the bkill command) any interactive jobs that are running
* logout from your session prior to the maintenance window
You may login and resubmit your jobs from Monday, 30 March 2026.
Users will receive a notification seven days prior to the maintenance window, advising that the bigmem and long queues will be closed or drained in preparation for the scheduled downtime.
Users will receive another notification 24 hours prior to the maintenance window, advising that the short/medium and interactive queues will be closed or drained in preparation for the scheduled downtime.
We apologise for any inconvenience this may cause.
Best Wishes,
Genomics England
Feb 27, 2026 - 12:23 GMT
The Double Helix HPC will not be available on Sunday, 29 March 2026 from 10:00 (GMT) to 12:00 (GMT).
Logins will not be possible during this time and running interactive jobs will be affected, any jobs that are still running at the start of the maintenance window will be terminated and will need to be rerun. This will include any orchestration jobs you may have running for your workflows.
In preparation please:
* save any ongoing work
* terminate (using the bkill command) any interactive jobs that are running
* logout from your session prior to the maintenance window
You may login and resubmit your jobs from Monday, 30 March 2026.
Users will receive a notification seven days prior to the maintenance window, advising that the bigmem and long queues will be closed or drained in preparation for the scheduled downtime.
Users will receive another notification 24 hours prior to the maintenance window, advising that the short/medium and interactive queues will be closed or drained in preparation for the scheduled downtime.
We apologise for any inconvenience this may cause.
Best Wishes,
Genomics England
Feb 27, 2026 - 12:23 GMT