In progress - Scheduled maintenance is currently in progress. We will provide updates as necessary.
Apr 30, 2026 - 09:00 BST
Scheduled - Dear Users,

We would like to inform you of a planned release being deployed for CloudOS.

SW 6.4 Elder Release will be deployed on Thursday, 30 April 2026 between 09:00 (BST) and 18:00 (BST).

Please note that we cannot ensure the normal functionality of the CloudOS application during this time.

This release will include 14 new features for CloudOS, including:
- Revamped Navigation for Federated Data, Data Science and Advanced Analytics
- Interactive Sessions through the Lifebit CLI
- Linked Folders in Snapshots and RShiny Apps
- Simplified Data Adding for Interactive Sessions
- Expanded Nextflow Version Support
- Deprecation of Community Tools

If you have any issues following this release, please let us know by raising a Service Desk ticket.

We apologise in advance for any inconvenience caused by this upgrade.

Best wishes,
Genomics England

Apr 30, 2026 09:00-18:00 BST
General_Service_Updates_Genomics_England Operational
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NGIS_Production_Environment Operational
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General_Service_Updates_NGIS_Production Operational
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NGIS_PROD_Test_Selection Operational
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NGIS_PROD_Test_Ordering Operational
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NGIS_PROD_SFTP Operational
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NGIS_PROD_M.I.Portal Operational
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NGIS_PROD_Interpretation_Portal Operational
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NGIS_PROD_CIP-API Operational
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NGIS_PROD_CVA Operational
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NGIS_PROD_IGV Operational
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NGIS_PROD_Congenica Operational
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NGIS_PROD_Cancer_DSS Operational
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NGIS_UAT_Environment Operational
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General_Service_Updates_NGIS_UAT Operational
NGIS_UAT_Test_Selection Operational
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NGIS_UAT_Test_Ordering Operational
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NGIS_UAT_SFTP Operational
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NGIS_UAT_M.I.Portal Operational
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NGIS_UAT_Interpretation_Portal Operational
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NGIS_UAT_CIP_API Operational
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NGIS_UAT_CVA Operational
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NGIS_UAT_IGV Operational
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NGIS_UAT_Congenica Operational
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NGIS_UAT_Cancer_DSS Operational
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Third Party Integrator Operational
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Third Party Integrator - Production Operational
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Third Party Integrator - UAT Operational
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Third Party Integrator - SIT Operational
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100K_Applications Operational
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100K_Interpretation_Portal Operational
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100K_CIP-API Operational
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100K_SNP Operational
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100K_Congenica Operational
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100K_MI_Portal Operational
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General_Service_Updates_100K_Applications Operational
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100K_Labkey Operational
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100K_Open_Clinica Operational
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Cloud_RE Under Maintenance
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General_Service_Updates_Cloud_RE Under Maintenance
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CloudOS Under Maintenance
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VDI Operational
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AWS_Workspace Operational
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Research_Environment Operational
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General_Service_Updates_Research_Environment Operational
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RE_Confluence Operational
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RE_Labkey Operational
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RE_Data_Discovery_Portal Operational
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RE_High_Performance_Compute_HPC_HELIX Operational
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RE_Participant_Explorer Operational
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RE_Research_Portal Operational
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RE_IVA Operational
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RE_Airlock_MFT Operational
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Atlassian_Suite Operational
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GE_Jira_Service_Desk Operational
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GE_Jira Operational
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GE_Confluence Operational
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PanelApp Operational
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Generation Study (Newborns) Operational
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Generation Study Portal Operational
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Generation Study Website Operational
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Generation Study CRM Operational
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Variant Review Tool Operational
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Newborns Pipeline Operational
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Tableau Operational
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Tableau_Production_Internal Operational
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Tableau_Production_External (Coming Soon) Operational
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Aspera Operational
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Aspera Operational
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GitLab Operational
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GitLab Operational
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Artifactory Operational
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Artifactory Operational
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WEKA Storage Platform Operational
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WEKA Operational
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Colt Operational
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Lumen Internet Connectivity Operational
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Manage Engine Operational
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Manage Engine (Self-Service) Operational
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Manage Engine (AD Manager Plus) Operational
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Semarchy Operational
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Semarchy Master Data Management Operational
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Quantum ObjectStore Operational
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Quantum ObjectStore Operational
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Miro Application Operational
Miro Log in ability Operational
Miro Mail System Operational
Miro Web Site Operational
AWS VPN Operational
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Operational
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Partial Outage
Major Outage
Maintenance
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No downtime recorded on this day.
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Scheduled Maintenance

NGIS Production Environment: Congenica Case Deletion - 30 April 2026 Apr 30, 2026 09:00-17:00 BST

Dear Congenica User,

This is a reminder that GEL will be deleting cases from Congenica on a regular basis. The cases that will be marked for deletion will be the ones that have been closed for 2 weeks in the Interpretation Portal, this is regardless of the amount of time that it has been in Congenica. Closed is defined as the report/summary of findings and exit questionnaire being completed by the user.

The next set of deletions will take place on the Thursday, 30 April 2026.

If you wish to keep a case in Congenica, we advise that you inform the Genomics England Service Desk at least 3 days in advance of the 2 week mark for your case.

Posted on Apr 16, 2026 - 11:52 BST

NGIS Production Environment: Regulus Increment 1.4 and Congenica v4.2 Release Notification May 6, 2026 17:00-21:00 BST

Dear all,

We would like to inform you of software releases in the NGIS production environment. Regulus Increment 1.4 and Congenica v4.2 will be released on Wednesday, 06 May 2026 from 17:00 (BST) to 21:00 (BST).

The main changes in the Regulus Increment 1.4 release are:
- Gene panel updates to align to Test Directory v9
- Bug fixes

The main changes in the Congenica v4.2 release are:
- Exomiser Upgrade
The platform’s variant prioritization pipeline has been upgraded from Exomiser v12 to
v14.1.
- HPO Reference Dataset Update
The internal Human Phenotype Ontology (HPO) database has been updated to the 2025-11-24 Release. The platform now supports searching and submitting all HPO terms included in this version.
- Bug Fixes

The Regulus Increment 1.4 Release Note and the Congenica v4.2 Release Noteare now available in the 'GEL Release Documentation' folder in NHS Futures.

Please note that all applications in the NGIS production environment will be unavailable within this timeframe.

Posted on Apr 29, 2026 - 13:07 BST
May 1, 2026

No incidents reported today.

Apr 30, 2026

Unresolved incident: Research Environment - Maintenance Notification - CloudOS Data Release.

Apr 29, 2026
Resolved - This incident has been resolved.
Apr 29, 19:19 BST
Investigating - We are currently investigating this issue.
Apr 29, 19:07 BST
Apr 28, 2026
Completed - The scheduled maintenance has been completed.
Apr 28, 14:00 BST
In progress - Scheduled maintenance is currently in progress. We will provide updates as necessary.
Apr 28, 10:00 BST
Scheduled - Dear all,

We would like to inform you of an outage on the NGIS UAT environment, to implement a software release to Congenica. The outage will be on Tuesday, 28 April 2026 from 10:00 (BST) to 14:00 (BST).

The Congenica v4.2 Release Note is available in the 'GEL Release Documentation' folder in NHS Futures.

The main changes in this release are:

- Exomiser Upgrade
The platform’s variant prioritization pipeline has been upgraded from Exomiser v12 to
v14.1.
- HPO Reference Dataset Update
The internal Human Phenotype Ontology (HPO) database has been updated to the 2025-11-24 Release. The platform now supports searching and submitting all HPO terms included in this version.
- Bug Fixes

Please note that Congenica in the NGIS UAT environment will be unavailable during the advised timeframe. There will be no impact to NGIS production Congenica portal.

Apr 24, 13:22 BST
Apr 27, 2026

No incidents reported.

Apr 26, 2026

No incidents reported.

Apr 25, 2026

No incidents reported.

Apr 24, 2026

No incidents reported.

Apr 23, 2026

No incidents reported.

Apr 22, 2026
Completed - The scheduled maintenance has been completed.
Apr 22, 21:00 BST
In progress - Scheduled maintenance is currently in progress. We will provide updates as necessary.
Apr 22, 17:01 BST
Scheduled - Dear all,

We would like to inform you of planned maintenance and a software release for Cancer DSS in the NGIS production environment. CDSSv6.18.0 will be released on Wednesday, 22 April 2026 from 17:00 (BST) to 21:00 (BST).

The CDSSv6.18.0 Release Note is now available in the 'GEL Release Documentation' folder in NHS Futures.

The main changes in the CDSSv6.18.0 release are:
- Ability to support 100k frequency data display in cDSS
- Bug fixes related to filtering and usability improvements

Please note that all applications the NGIS production environment will be unavailable during this timeframe.

Apr 15, 17:11 BST
Completed - The scheduled maintenance has been completed.
Apr 22, 17:00 BST
In progress - Scheduled maintenance is currently in progress. We will provide updates as necessary.
Apr 22, 13:00 BST
Scheduled - Dear all,

We would like to inform you of a planned data release for PanelApp in the NGIS UAT environment. Regulus Increment 1.4 will be released on Wednesday, 22 April 2026 from 13:00 (BST) to 17:00 (BST).

The Regulus Increment 1.4 Release Note is now available in the 'GEL Release Documentation' folder in NHS Futures.

The main change in the Regulus Increment 1.4 release is:
- Gene panel updates to align to Test Directory v9

Please note that there is no impact to the NGIS production environment during this timeframe.

Apr 20, 16:46 BST
Apr 21, 2026

No incidents reported.

Apr 20, 2026

No incidents reported.

Apr 19, 2026

No incidents reported.

Apr 18, 2026

No incidents reported.

Apr 17, 2026

No incidents reported.